Isshiki Otsutsuki was a member of the Otsutsuki clan’s main family and the leader of Kara.

Isshiki was a hypocrite and an abusive parental figure, as when he took in Kawaki as an adopted son and promised him safety, he placed the child, alongside fourteen others, in a dangerous experiment that led to thirteen of them dying outright. His methods of training Kawaki in becoming his vessel, along with discipline for disobedience, amounted to constant physical abuse and neglect, beating the child while refusing to explain to him of the true purpose of the seal he placed onto him. Isshiki’s horrible parenting greatly warped Kawaki’s personality with violent tendencies and trauma.

Despite his amoral nature, Isshiki was shown to be able to remain calm even when faced with insult. Generally, Isshiki was formal and courteous, addressing the fellow members of his organisation politely, even extending manners to his enemies, as apologised for not removing his shoes when entering the Uzumaki household. He preferred to only incapacitate enemies when not needing to kill them and even willing to avoid conflict if potential adversaries were agreeable to his terms. At the same time, like Momoshiki, Isshiki’s confidence stems from an extreme superiority-complex. As such when faced against the prospect of an opponent who can actually challenge him, he becomes furious and determined to restore his self-perceived dominance.